Eddie Murphy says some of Hollywood’s most iconic films would have looked very different if he had not turned down roles that later became global hits. Speaking in a new interview, the legendary comedian reflected on the parts he regrets passing on, calling three titles the biggest “wish I would have done” movies of his career.

Murphy confirmed that he had opportunities to appear in Ghostbusters, Rush Hour and Who Framed Roger Rabbit, all of which went on to become box-office successes and cultural staples. He explained that timing conflicts, creative differences, and career priorities at the time pulled him in different directions, even though the scripts crossed his desk before the films were made.

The actor said he was originally eyed for a spot in the Ghostbusters lineup during the early 1980s while filming Beverly Hills Cop, one of his earliest career-defining roles. The schedules clashed, so he chose to stick with Axel Foley. Looking back, he said the choice still lingers as one of his biggest “what ifs”.

Murphy also discussed turning down Who Framed Roger Rabbit, the groundbreaking 1988 live-action and animation hybrid that went on to win three Oscars. He said the creative ambition of the project was ahead of its time but he did not understand the vision back then.

The third film on his list, Rush Hour, ended up becoming the breakout franchise for Jackie Chan and Chris Tucker. Murphy confirmed that he was initially approached for the role that later went to Tucker, calling it another moment when he simply chose a different direction.

Even with a career spanning decades of global hits, Murphy said the missed opportunities still fascinate him because of how profoundly those movies shaped Hollywood comedy. He added that he is grateful for the path he chose but enjoys revisiting the “alternate timeline” of the roles that got away.

Murphy is currently promoting new projects but says reflecting on the past has become part of understanding the evolution of his career and comedy legacy.